Conversely, patients with progressive exertional breathlessness and worsening oedema who often have pulmonary hypertension, a low cardiac output and worsening renal dysfunction are often difficult to manage ger prescriptions online for proscar Recently, two SNPs in the 3 untranslated region UTR of the SULT1A1 gene, rs6839 and rs1042157, have been associated with decreased SULT1A1 activity